2023-07-31 Mon 22:16 [[John Ioannidis 2005 - Why Most Published Research Findings Are False.pdf]] >%% >```annotation-json >{"created":"2023-08-01T05:17:49.606Z","updated":"2023-08-01T05:17:49.606Z","document":{"title":"PLME0208_696-701.indd","link":[{"href":"urn:x-pdf:9f8cefa0a31f02faf408f0de1c18b3eb"},{"href":"vault:/1-pub/A/John Ioannidis 2005 - Why Most Published Research Findings Are False.pdf"}],"documentFingerprint":"9f8cefa0a31f02faf408f0de1c18b3eb"},"uri":"vault:/1-pub/A/John Ioannidis 2005 - Why Most Published Research Findings Are False.pdf","target":[{"source":"vault:/1-pub/A/John Ioannidis 2005 - Why Most Published Research Findings Are False.pdf","selector":[{"type":"TextPositionSelector","start":5579,"end":5837},{"type":"TextQuoteSelector","exact":"Simulations show that for most study designs and settings, it is more likely for a research claim to be false than true. Moreover, for many current scientifi c fi elds, claimed research fi ndings may often be simply accurate measures of the prevailing bias. ","prefix":"e of statistical signifi cance. ","suffix":"In this essay, I discuss the imp"}]}]} >``` >%% >*%%PREFIX%%e of statistical signifi cance.%%HIGHLIGHT%% ==Simulations show that for most study designs and settings, it is more likely for a research claim to be false than true. Moreover, for many current scientifi c fi elds, claimed research fi ndings may often be simply accurate measures of the prevailing bias.== %%POSTFIX%%In this essay, I discuss the imp* >%%LINK%%[[#^givd0j0xq97|show annotation]] >%%COMMENT%% > >%%TAGS%% > ^givd0j0xq97 >%% >```annotation-json >{"created":"2023-08-01T22:10:05.613Z","updated":"2023-08-01T22:10:05.613Z","document":{"title":"PLME0208_696-701.indd","link":[{"href":"urn:x-pdf:9f8cefa0a31f02faf408f0de1c18b3eb"},{"href":"vault:/1-pub/A/John Ioannidis 2005 - Why Most Published Research Findings Are False.pdf"}],"documentFingerprint":"9f8cefa0a31f02faf408f0de1c18b3eb"},"uri":"vault:/1-pub/A/John Ioannidis 2005 - Why Most Published Research Findings Are False.pdf","target":[{"source":"vault:/1-pub/A/John Ioannidis 2005 - Why Most Published Research Findings Are False.pdf","selector":[{"type":"TextPositionSelector","start":5112,"end":5578},{"type":"TextQuoteSelector","exact":" a research fi nding is less likely to be true when the studies conducted in a fi eld are smaller; when effect sizes are smaller; when there is a greater number and lesser preselection of tested relationships; where there is greater fl exibility in designs, defi nitions, outcomes, and analytical modes; when there is greater fi nancial and other interest and prejudice; and when more teams are involved in a scientifi c fi eld in chase of statistical signifi cance.","prefix":"ifi c fi eld. In this framework,","suffix":" Simulations show that for most "}]}]} >``` >%% >*%%PREFIX%%ifi c fi eld. In this framework,%%HIGHLIGHT%% ==a research fi nding is less likely to be true when the studies conducted in a fi eld are smaller; when effect sizes are smaller; when there is a greater number and lesser preselection of tested relationships; where there is greater fl exibility in designs, defi nitions, outcomes, and analytical modes; when there is greater fi nancial and other interest and prejudice; and when more teams are involved in a scientifi c fi eld in chase of statistical signifi cance.== %%POSTFIX%%Simulations show that for most* >%%LINK%%[[#^6rbny9bjebi|show annotation]] >%%COMMENT%% > >%%TAGS%% > ^6rbny9bjebi